Non Destructive Evaporation Technology Improves Crystallisation Control

eXalt Technology

Ipswich, UK & Stone Ridge NY, USA — Genevac announces eXalt, an exciting new non-destructive evaporation technology developed with partners in the field of pharmaceutical small molecule crystallisation.

eXalt has found application in labs that perform tasks including:

  • first time crystallisation of amorphous forms,
  • re-crystallisation of samples which have only a few known forms,
  • removing a hydrate,
  • solvent screening studies to find the most suitable conditions to take forward in development,
  • high throughput co-crystallisation screens and
  • studies to confirm stable isoforms.

eXalt enables a wide range of solvents and multiple actives to be evaporated all at the same slow rate, and under the same conditions, giving the user unprecedented control of the crystallisation process.

This is achieved using a special holder which allows a can be configured to slow the evaporation rate each solvent, i.e. the more volatile solvents are impeded more, and some solvents such as water, need no restriction.

The holder is then placed in the controlled conditions of a Genevac HT Series Evaporator which cycles the pressure over the samples to create a draw, achieving controlled, even evaporation.

eXalt holders can accept up to 24 different samples, and 4 8 or 12 holders can be placed in the evaporator, depending on size.

To review a web presentation summarising eXalt technology, how it works together with some user experiences and results please visit

For further information please contact Genevac on telephone 44-1473-240000 / +44-1473-240000 / +1-845-255-5000 or email

Worldwide HQ
Genevac Ltd.
Farthing Road
Ipswich IP1 5AP

tel: +44-1473-240000

North America HQ
SP Scientific
3538 Main Street
P.O Box 158
Stone Ridge NY 12484 USA

Tel: +1.845.687.5315

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